Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hisC-2Aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: pfo:Pfl_4075 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa)    
Predicted Functional Partners:
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: aba:Acid345_3685 imidazoleglycerol-phosphate dehydratase.
 
 0.996
Acid_7884
PFAM: Prephenate dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: aba:Acid345_1162 prephenate dehydrogenase.
 
 
 0.980
Acid_4167
KEGG: sru:SRU_1370 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
    
 0.978
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.962
Acid_7054
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: aba:Acid345_2043 prephenate dehydratase.
  
 
 0.921
Acid_4098
Phenylalanine 4-hydroxylase; PFAM: aromatic amino acid hydroxylase; KEGG: bur:Bcep18194_A3259 phenylalanine-4-hydroxylase, monomeric form.
     
 0.913
Acid_5790
PFAM: inositol monophosphatase; KEGG: cdi:DIP0744 hypothetical protein.
  
 
 0.911
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.907
Acid_3849
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis; KEGG: aba:Acid345_3688 histidine biosynthesis.
  
 0.902
Acid_6369
Tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_3931 tryptophanase.
     
 0.901
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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