node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0181 | Acid_1039 | Acid_0181 | Acid_1039 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | 0.999 |
Acid_0181 | Acid_2458 | Acid_0181 | Acid_2458 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | 0.892 |
Acid_0181 | Acid_3181 | Acid_0181 | Acid_3181 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.930 |
Acid_0181 | hemA | Acid_0181 | Acid_3178 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.774 |
Acid_0181 | hemC | Acid_0181 | Acid_3179 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.991 |
Acid_0181 | hemE | Acid_0181 | Acid_5202 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.918 |
Acid_0181 | hemL | Acid_0181 | Acid_4251 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.743 |
Acid_0743 | Acid_1327 | Acid_0743 | Acid_1327 | 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: beta-ketoacyl synthase; KEGG: rru:Rru_A0045 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | PFAM: AMP-dependent synthetase and ligase; KEGG: sma:SAV377 putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase. | 0.621 |
Acid_0743 | hemL | Acid_0743 | Acid_4251 | 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: beta-ketoacyl synthase; KEGG: rru:Rru_A0045 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.737 |
Acid_1039 | Acid_0181 | Acid_1039 | Acid_0181 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | 0.999 |
Acid_1039 | Acid_2458 | Acid_1039 | Acid_2458 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | 0.722 |
Acid_1039 | Acid_3181 | Acid_1039 | Acid_3181 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.999 |
Acid_1039 | hemA | Acid_1039 | Acid_3178 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.600 |
Acid_1039 | hemC | Acid_1039 | Acid_3179 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.783 |
Acid_1039 | hemL | Acid_1039 | Acid_4251 | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.847 |
Acid_1327 | Acid_0743 | Acid_1327 | Acid_0743 | PFAM: AMP-dependent synthetase and ligase; KEGG: sma:SAV377 putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase. | 3-oxoacyl-[acyl-carrier-protein] synthase II; PFAM: beta-ketoacyl synthase; KEGG: rru:Rru_A0045 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.621 |
Acid_1327 | hemL | Acid_1327 | Acid_4251 | PFAM: AMP-dependent synthetase and ligase; KEGG: sma:SAV377 putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde-2,1-aminomutase. | 0.620 |
Acid_2458 | Acid_0181 | Acid_2458 | Acid_0181 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: aae:aq_207 uroporphyrin-III C-methyltransferase. | 0.892 |
Acid_2458 | Acid_1039 | Acid_2458 | Acid_1039 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | TIGRFAM: siroheme synthase; KEGG: mta:Moth_1251 siroheme synthase, N-terminal domain. | 0.722 |
Acid_2458 | Acid_3181 | Acid_2458 | Acid_3181 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aba:Acid345_4300 porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sat:SYN_02272 uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase. | 0.989 |