| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acid_6154 | Acid_6995 | Acid_6154 | Acid_6995 | Dihydroorotase; PFAM: amidohydrolase; KEGG: mlo:mll4451 dihydroorotase. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.900 |
| Acid_6154 | pyrB | Acid_6154 | Acid_5512 | Dihydroorotase; PFAM: amidohydrolase; KEGG: mlo:mll4451 dihydroorotase. | KEGG: pca:Pcar_1615 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.900 |
| Acid_6154 | pyrC | Acid_6154 | Acid_5513 | Dihydroorotase; PFAM: amidohydrolase; KEGG: mlo:mll4451 dihydroorotase. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.904 |
| Acid_6154 | pyrD | Acid_6154 | Acid_4402 | Dihydroorotase; PFAM: amidohydrolase; KEGG: mlo:mll4451 dihydroorotase. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.900 |
| Acid_6995 | Acid_6154 | Acid_6995 | Acid_6154 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotase; PFAM: amidohydrolase; KEGG: mlo:mll4451 dihydroorotase. | 0.900 |
| Acid_6995 | allB | Acid_6995 | Acid_0362 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | 0.768 |
| Acid_6995 | carA | Acid_6995 | Acid_2394 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: aba:Acid345_2194 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.847 |
| Acid_6995 | carB | Acid_6995 | Acid_2395 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: aba:Acid345_2197 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.876 |
| Acid_6995 | pyrB | Acid_6995 | Acid_5512 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | KEGG: pca:Pcar_1615 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.854 |
| Acid_6995 | pyrC | Acid_6995 | Acid_5513 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.975 |
| Acid_6995 | pyrD | Acid_6995 | Acid_4402 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.900 |
| Acid_6995 | pyrE | Acid_6995 | Acid_4993 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.979 |
| Acid_6995 | pyrE-2 | Acid_6995 | Acid_7287 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.979 |
| Acid_6995 | pyrF | Acid_6995 | Acid_4724 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.854 |
| allB | Acid_6995 | Acid_0362 | Acid_6995 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.768 |
| allB | carA | Acid_0362 | Acid_2394 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: aba:Acid345_2194 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.986 |
| allB | carB | Acid_0362 | Acid_2395 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: aba:Acid345_2197 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.986 |
| allB | pyrB | Acid_0362 | Acid_5512 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | KEGG: pca:Pcar_1615 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.998 |
| allB | pyrD | Acid_0362 | Acid_4402 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.845 |
| allB | pyrE | Acid_0362 | Acid_4993 | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.799 |