Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acid_4983L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (527 aa)    
Predicted Functional Partners:
Acid_7243
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; dihydroorotate dehydrogenase; KEGG: mlo:mll4732 glycolate oxidase, (S)-2-hydroxy-acid oxidase, peroxisomal.
  
 0.828
Acid_1641
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: cme:CMQ436C glycolate oxidase, peroxysomal.
  
 0.822
Acid_1779
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: ath:At4g18360 (S)-2-hydroxy-acid oxidase, peroxisomal, putative / glycolate oxidase, putative / short chain alpha-hydroxy acid oxidase, putative.
  
 0.818
Acid_4982
PFAM: AMP-dependent synthetase and ligase; KEGG: gka:GK0693 AMP-binding enzyme.
       0.773
Acid_2058
FAD linked oxidase domain protein; PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: noc:Noc_0464 hypothetical protein.
 
  
 0.678
Acid_5761
PFAM: protein of unknown function DUF162; KEGG: dde:Dde_1844 hypothetical protein.
 
   
 0.600
Acid_5762
TIGRFAM: iron-sulfur cluster binding protein; KEGG: rxy:Rxyl_2994 iron-sulfur cluster binding protein.
 
   
 0.594
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.536
Acid_5763
PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: bsu:BG12447 similar to glycolate oxidase.
 
  
 0.509
Acid_4980
PFAM: arsenate reductase and related; KEGG: dra:DR0136 hypothetical protein; Belongs to the ArsC family.
       0.483
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
Server load: low (12%) [HD]