STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acid_5133PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: tko:TK1966 D-3-phosphoglycerate dehydrogenase. (312 aa)    
Predicted Functional Partners:
Acid_1855
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: lic:LIC10838 glyoxalase.
 
      0.821
Acid_7115
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase.
   
 
 0.709
Acid_5130
PFAM: beta-lactamase domain protein; KEGG: aba:Acid345_3880 beta-lactamase-like.
     
 0.567
Acid_3182
PFAM: phosphoribulokinase/uridine kinase; KEGG: aba:Acid345_3054 uridine kinase; Belongs to the uridine kinase family.
   
  0.566
Acid_5132
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
     
 0.565
Acid_5131
PFAM: GCN5-related N-acetyltransferase; KEGG: aba:Acid345_4636 GCN5-related N-acetyltransferase.
       0.561
Acid_5128
KEGG: mca:MCA1289 hypothetical protein.
       0.557
Acid_5129
Hypothetical protein.
       0.557
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
 
 0.523
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.491
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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