STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa)    
Predicted Functional Partners:
Acid_7115
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: aba:Acid345_3426 homocysteine S-methyltransferase.
  
 
 0.987
Acid_0253
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: bja:bll5948 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
 0.966
Acid_2676
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase.
  
 0.966
Acid_3332
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: sso:SSO0407 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase.
  
 0.966
Acid_4184
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.943
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.941
Acid_1686
PFAM: S-adenosylmethionine synthetase; KEGG: dge:Dgeo_0287 methionine adenosyltransferase.
  
  
 
0.926
Acid_1689
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ana:alr4173 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.923
Acid_1700
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ana:alr4173 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.923
Acid_2673
PFAM: homocysteine S-methyltransferase; KEGG: gsu:GSU2921 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation.
  
 
 0.919
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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