STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acid_5369CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: sat:SYN_00963 chemotaxis protein. (676 aa)    
Predicted Functional Partners:
Acid_5070
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 0.999
Acid_5368
PFAM: CheW domain protein; KEGG: sat:SYN_00975 chemotaxis protein.
 0.999
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.999
Acid_5372
PFAM: response regulator receiver; KEGG: sat:SYN_00967 chemotaxis protein.
 
 0.998
Acid_1069
PFAM: chemotaxis sensory transducer; KEGG: tdn:Tmden_0972 methyl-accepting chemotaxis sensory transducer.
 
 0.997
Acid_2138
PFAM: chemotaxis sensory transducer; KEGG: bba:Bd1340 putative methyl accepting chemotaxis protein.
 
 0.997
Acid_3416
PFAM: chemotaxis sensory transducer; KEGG: sat:SYN_00971 methyl-accepting chemotaxis protein.
 
 0.997
Acid_5742
PFAM: chemotaxis sensory transducer; KEGG: sat:SYN_00971 methyl-accepting chemotaxis protein.
 
 0.997
cheD
CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.993
Acid_5370
PFAM: MCP methyltransferase, CheR-type; KEGG: sat:SYN_00970 chemotaxis protein methyltransferase.
 
  
 0.992
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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