STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (312 aa)    
Predicted Functional Partners:
Acid_4067
2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; KEGG: chy:CHY_0521 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 0.997
Acid_5704
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 0.993
Acid_0177
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: pca:Pcar_1007 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 0.978
ilvD
KEGG: rxy:Rxyl_1326 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
  
 0.974
Acid_2937
Pyruvate dehydrogenase (acetyl-transferring); PFAM: Transketolase, central region; Transketolase domain protein; KEGG: sru:SRU_0576 2-oxoisovalerate dehydrogenase, E1 component, alpha and beta subunit.
  
 0.947
Acid_3687
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: aba:Acid345_1786 dehydrogenase, E1 component.
  
 0.947
Acid_0353
PFAM: Transketolase, central region; Transketolase domain protein; KEGG: oih:OB1865 branched-chain alpha-keto acid dehydrogenase E1 beta chain (3-methyl-2-oxobutanoate dehydrogenase (lipoamide)).
  
 0.924
Acid_7670
PFAM: aminotransferase, class IV; KEGG: hch:HCH_06836 branched-chain amino acid aminotransferase.
  
  
 
0.924
Acid_3250
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tte:TTE1574 cystathionine gamma-synthase.
   
 0.919
Acid_5643
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: aba:Acid345_1913 cystathionine gamma-synthase.
   
 0.919
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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