STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. (290 aa)    
Predicted Functional Partners:
Acid_6730
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bja:bll4069 exodeoxyribonuclease III.
    
 
 0.895
nth
DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.846
Acid_5985
KEGG: mag:amb0240 hypothetical protein.
       0.714
Acid_0126
KEGG: tel:tll1975 hypothetical protein.
      0.658
Acid_1072
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.546
Acid_7406
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: gme:Gmet_3187 DNA polymerase B, exonuclease.
    
 
 0.467
Acid_1040
SMART: helicase c2; DEAD-like helicases-like; KEGG: aba:Acid345_4634 helicase C2.
 
  
 0.461
Acid_7732
DNA topoisomerase III; KEGG: cac:CAC3567 topoisomerase B; TIGRFAM: ATP-dependent DNA helicase, RecQ family; DNA topoisomerase III; PFAM: helicase domain protein; HRDC domain protein; TOPRIM domain protein; DEAD/DEAH box helicase domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DEAD-like helicases-like.
  
 
 0.459
Acid_5497
PFAM: ribonuclease II; RNA binding S1 domain protein; KEGG: cte:CT1000 ribonuclease II family protein.
  
   
 0.447
Acid_2123
PFAM: glycoside hydrolase 15-related; KEGG: glycosyl hydrolase, family 15.
 
      0.442
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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