STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEH90605.1Bifunctional aconitate hydratase2/2-methylisocitrate dehydratase. (325 aa)    
Predicted Functional Partners:
SEH81719.1
2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 
 0.923
sucC
succinyl-CoA synthetase (ADP-forming) betasubunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.922
SEH57713.1
Tartrate/fumarate subfamily Fe-S typehydro-lyase subunit alpha; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.775
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.711
SEH83211.1
Dihydrolipoamide dehydrogenase.
   
 
 0.675
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 
0.610
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
     
 0.592
SEH74460.1
Adenylylsulfate reductase subunit alpha.
   
  
 0.580
SEH83194.1
Pyruvate dehydrogenasedihydrolipoyltransacetylase subunit.
   
 
 0.527
SEH82558.1
Cbb3-type cytochrome c oxidase subunit I; Belongs to the heme-copper respiratory oxidase family.
   
    0.508
Your Current Organism:
Bathymodiolus azoricus
NCBI taxonomy Id: 235205
Other names: B. azoricus thioautotrophic gill symbiont, Bathymodiolus azoricus thioautotrophic gill symbiont
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