node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH58163.1 | SEH58181.1 | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00007_4 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylformylglycinamidine synthase. | 0.999 |
SEH58163.1 | SEH77378.1 | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00059_8 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.975 |
SEH58163.1 | glyA | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00098_3 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.975 |
SEH58163.1 | purC | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00006_25 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylaminoimidazole-succinocarboxamides ynthase; Belongs to the SAICAR synthetase family. | 0.993 |
SEH58163.1 | purD | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00021_10 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.993 |
SEH58163.1 | purE | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00019_24 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylaminoimidazole carboxylasecatalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.976 |
SEH58163.1 | purF | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00022_10 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.993 |
SEH58163.1 | purH | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00119_0 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Purine biosynthesis protein purH. | 0.992 |
SEH58163.1 | purM | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00016_18 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylaminoimidazole synthetase. | 0.992 |
SEH58163.1 | purN | BAZSYMB_SCAFFOLD00007_3 | BAZSYMB_SCAFFOLD00016_17 | Phosphoribosylformylglycinamidine (FGAM)synthase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.993 |
SEH58181.1 | SEH58163.1 | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00007_3 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylformylglycinamidine (FGAM)synthase. | 0.999 |
SEH58181.1 | SEH77378.1 | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00059_8 | Phosphoribosylformylglycinamidine synthase. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.975 |
SEH58181.1 | glyA | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00098_3 | Phosphoribosylformylglycinamidine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.975 |
SEH58181.1 | purC | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00006_25 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole-succinocarboxamides ynthase; Belongs to the SAICAR synthetase family. | 0.994 |
SEH58181.1 | purD | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00021_10 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.993 |
SEH58181.1 | purE | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00019_24 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole carboxylasecatalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.976 |
SEH58181.1 | purF | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00022_10 | Phosphoribosylformylglycinamidine synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.993 |
SEH58181.1 | purH | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00119_0 | Phosphoribosylformylglycinamidine synthase. | Purine biosynthesis protein purH. | 0.992 |
SEH58181.1 | purM | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00016_18 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylaminoimidazole synthetase. | 0.996 |
SEH58181.1 | purN | BAZSYMB_SCAFFOLD00007_4 | BAZSYMB_SCAFFOLD00016_17 | Phosphoribosylformylglycinamidine synthase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.996 |