Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HH_1007Ubiquinol cytochrome C oxidoreductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (169 aa)    
Predicted Functional Partners:
HH_1005
Conserved hypothetical protein; Similar to two-component response regulator proteins.
 
 0.999
HH_1006
Ubiquinol cytochrome c oxidoreductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 0.999
fixP
Cb-type cytochrome C oxidase subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
 0.996
nuoD
Donor-ubiquinone reductase I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
 0.986
nuoC
Donor-ubiquinone reductase I; Subunit C.
   
 0.979
frdB
Fumarate reductase; Iron-sulfur protein FrdB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.957
nuoB
Donor-ubiquinone reductase I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 0.957
frdA
Fumarate reductase; Flavoprotein component FrdA.
  
 
 0.956
HH_1365
Conserved hypothetical protein; Predicted secreted protein.
  
 0.950
fixO
Cb-type cytochrome C oxidase subunit II.
  
 0.944
Your Current Organism:
Helicobacter hepaticus
NCBI taxonomy Id: 235279
Other names: H. hepaticus ATCC 51449, Helicobacter hepaticus ATCC 51449, Helicobacter hepaticus str. ATCC 51449
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.