Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HH_1663Conserved hypothetical protein; Similar to Campylobacter jejuni CJ0404; predicted transmembrane protein. (308 aa)    
Predicted Functional Partners:
HH_1660
Conserved hypothetical protein; Possible UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
       0.823
wbpB
Lipopolysaccharide biosynthesis protein wbpB.
       0.823
HH_1661
Conserved hypothetical protein; Possible acyltransferase.
       0.820
HH_1664
Conserved hypothetical protein; Similar to Helicobacter pylori HP0184.
       0.716
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.709
lysS
lysyl-tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.709
HH_1667
Conserved hypothetical protein; Similar to Helicobacter pylori HP0181; predicted membrane-associated.
       0.699
folC
Folylpolyglutamate synthase.
  
    0.561
HH_1821
Conserved hypothetical protein; Predicted lipoprotein.
     
 0.515
fliA
RNA polymerase sigma 28 factor; Belongs to the sigma-70 factor family.
  
 
 0.421
Your Current Organism:
Helicobacter hepaticus
NCBI taxonomy Id: 235279
Other names: H. hepaticus ATCC 51449, Helicobacter hepaticus ATCC 51449, Helicobacter hepaticus str. ATCC 51449
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