STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HH_1682Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (222 aa)    
Predicted Functional Partners:
HH_1683
Predicted secreted protein.
       0.832
pgsA
Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.827
HH_1681
Conserved hypothetical protein; Similar to Campylobacter jejuni CJ1068; predicted metallopeptidase.
       0.825
HH_1684
Hypothetical protein.
       0.758
HH_1685
Conserved hypothetical protein; Similar to Campylobacter jejuni CJ0984; Belongs to the UPF0246 family.
       0.737
HH_0214
Conserved hypothetical protein.
  
  
 0.698
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
     0.627
HH_0581
Conserved hypothetical protein; Similar to Campylobacter jejuni integral membrane protein CJ0844c.
  
  
 0.620
HH_1283
S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
      0.612
corA
Mg and Co transporter; Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (By similarity). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity). Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
       0.608
Your Current Organism:
Helicobacter hepaticus
NCBI taxonomy Id: 235279
Other names: H. hepaticus ATCC 51449, Helicobacter hepaticus ATCC 51449, Helicobacter hepaticus str. ATCC 51449
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