STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)    
Predicted Functional Partners:
GK1301
2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) alpha subunit.
  
 
 0.978
GK2739
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.975
GK3019
Hypothetical conserved protein.
  
 0.956
GK1302
2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) beta subunit.
  
 
 0.940
GK1079
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.934
GK1440
Malic enzyme.
  
 0.931
GK1534
Malate dehydrogenase (malic enzyme).
  
 0.931
GK0426
Fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.928
GK2172
Aspartate transaminase (transaminase A).
  
 0.920
GK1059
Dehydrogenase E1 component, beta subunit (lipoamide).
   
 0.917
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.