node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0974 | GK0976 | GK0974 | GK0976 | Spore germination protein. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.461 |
GK0974 | queC | GK0974 | GK0975 | Spore germination protein. | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.461 |
GK0974 | queE | GK0974 | GK0977 | Spore germination protein. | Coenzyme PQQ synthesis; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.461 |
GK0976 | GK0974 | GK0976 | GK0974 | 6-pyruvoyl tetrahydrobiopterin synthase. | Spore germination protein. | 0.461 |
GK0976 | GK0979 | GK0976 | GK0979 | 6-pyruvoyl tetrahydrobiopterin synthase. | Semialdehyde dehydrogenase. | 0.451 |
GK0976 | GK1470 | GK0976 | GK1470 | 6-pyruvoyl tetrahydrobiopterin synthase. | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | 0.913 |
GK0976 | mtrA | GK0976 | GK2214 | 6-pyruvoyl tetrahydrobiopterin synthase. | GTP cyclohydrolaseI. | 0.983 |
GK0976 | queC | GK0976 | GK0975 | 6-pyruvoyl tetrahydrobiopterin synthase. | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.982 |
GK0976 | queE | GK0976 | GK0977 | 6-pyruvoyl tetrahydrobiopterin synthase. | Coenzyme PQQ synthesis; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
GK0976 | queF | GK0976 | GK0978 | 6-pyruvoyl tetrahydrobiopterin synthase. | Hypothetical conserved protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway. Is highly specific for its natural substrate preQ0, since it cannot use various aliphatic, aromatic and heterocyclic nitriles, although it can reduce the substrate analog 5- cyanopyrrolo[2,3-d]pyrimidin-4-one with lesser efficiency. Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.904 |
GK0976 | queG | GK0976 | GK0482 | 6-pyruvoyl tetrahydrobiopterin synthase. | Hypothetical conserved protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.417 |
GK0979 | GK0976 | GK0979 | GK0976 | Semialdehyde dehydrogenase. | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.451 |
GK0979 | queC | GK0979 | GK0975 | Semialdehyde dehydrogenase. | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.454 |
GK0979 | queE | GK0979 | GK0977 | Semialdehyde dehydrogenase. | Coenzyme PQQ synthesis; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.454 |
GK0979 | queF | GK0979 | GK0978 | Semialdehyde dehydrogenase. | Hypothetical conserved protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway. Is highly specific for its natural substrate preQ0, since it cannot use various aliphatic, aromatic and heterocyclic nitriles, although it can reduce the substrate analog 5- cyanopyrrolo[2,3-d]pyrimidin-4-one with lesser efficiency. Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.601 |
GK1470 | GK0976 | GK1470 | GK0976 | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | 6-pyruvoyl tetrahydrobiopterin synthase. | 0.913 |
GK1470 | mtrA | GK1470 | GK2214 | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | GTP cyclohydrolaseI. | 0.977 |
GK1470 | queC | GK1470 | GK0975 | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | Aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.824 |
GK1470 | queE | GK1470 | GK0977 | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | Coenzyme PQQ synthesis; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.985 |
GK1470 | queF | GK1470 | GK0978 | 6-pyruvoyltetrahydropterin synthase(PTP synthase). | Hypothetical conserved protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway. Is highly specific for its natural substrate preQ0, since it cannot use various aliphatic, aromatic and heterocyclic nitriles, although it can reduce the substrate analog 5- cyanopyrrolo[2,3-d]pyrimidin-4-one with lesser efficiency. Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.713 |