node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0680 | GK1203 | GK0680 | GK1203 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Type I signal peptidase; Belongs to the peptidase S26 family. | 0.904 |
GK0680 | lspA | GK0680 | GK1145 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.802 |
GK0680 | secDF | GK0680 | GK2582 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.726 |
GK0680 | tatC | GK0680 | GK0244 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Hypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.559 |
GK1144 | GK1146 | GK1144 | GK1146 | Hypothetical protein. | Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.535 |
GK1144 | lspA | GK1144 | GK1145 | Hypothetical protein. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.535 |
GK1146 | GK1144 | GK1146 | GK1144 | Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein. | 0.535 |
GK1146 | lspA | GK1146 | GK1145 | Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.893 |
GK1146 | pyrR | GK1146 | GK1147 | Hypothetical conserved protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.574 |
GK1203 | GK0680 | GK1203 | GK0680 | Type I signal peptidase; Belongs to the peptidase S26 family. | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | 0.904 |
GK1203 | lspA | GK1203 | GK1145 | Type I signal peptidase; Belongs to the peptidase S26 family. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.805 |
GK1203 | secDF | GK1203 | GK2582 | Type I signal peptidase; Belongs to the peptidase S26 family. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.726 |
GK1203 | tatC | GK1203 | GK0244 | Type I signal peptidase; Belongs to the peptidase S26 family. | Hypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.559 |
GK1838 | lspA | GK1838 | GK1145 | PTS system, fructose-specific enzyme II, BC component. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.555 |
ileS | lspA | GK1136 | GK1145 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.688 |
ileS | secDF | GK1136 | GK2582 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.767 |
lgt | lspA | GK3081 | GK1145 | Prolipoprotein diacylglyceryl transferase (Spore germination protein); Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.701 |
lgt | secDF | GK3081 | GK2582 | Prolipoprotein diacylglyceryl transferase (Spore germination protein); Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.650 |
lspA | GK0680 | GK1145 | GK0680 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | 0.802 |
lspA | GK1144 | GK1145 | GK1144 | Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Hypothetical protein. | 0.535 |