SEM38971.1 protein (Streptacidiphilus jiangxiensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SEM38971.1

Hypothetical protein. (427 aa)

Predicted Functional Partners:

SEM38901.1

0.971

SEM38890.1

0.958

SEM38871.1

0.928

SEM38988.1

0.878

SEM52182.1

0.823

SEM51932.1

0.823

SEM66069.1

0.778

SEM66104.1

0.772

SEK34722.1

0.759

SEK24635.1

0.744

Your Current Organism:

Streptacidiphilus jiangxiensis

NCBI taxonomy Id: 235985
Other names: JCM 12277, NBRC 100920, S. jiangxiensis, Streptacidiphilus jiangxiensis Huang et al. 2005, strain 33214

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEK24635.1	SEK34722.1	SAMN05414137_101228	SAMN05414137_101599	Xanthomonas XOO_2897-like deaminase.	Hypothetical protein.	0.775
SEK24635.1	SEM38871.1	SAMN05414137_101228	SAMN05414137_1263	Xanthomonas XOO_2897-like deaminase.	TraM recognition site of TraD and TraG.	0.482
SEK24635.1	SEM38890.1	SAMN05414137_101228	SAMN05414137_1264	Xanthomonas XOO_2897-like deaminase.	AAA-like domain-containing protein.	0.667
SEK24635.1	SEM38901.1	SAMN05414137_101228	SAMN05414137_1265	Xanthomonas XOO_2897-like deaminase.	Hypothetical protein.	0.761
SEK24635.1	SEM38971.1	SAMN05414137_101228	SAMN05414137_1266	Xanthomonas XOO_2897-like deaminase.	Hypothetical protein.	0.744
SEK34722.1	SEK24635.1	SAMN05414137_101599	SAMN05414137_101228	Hypothetical protein.	Xanthomonas XOO_2897-like deaminase.	0.775
SEK34722.1	SEM38871.1	SAMN05414137_101599	SAMN05414137_1263	Hypothetical protein.	TraM recognition site of TraD and TraG.	0.424
SEK34722.1	SEM38890.1	SAMN05414137_101599	SAMN05414137_1264	Hypothetical protein.	AAA-like domain-containing protein.	0.742
SEK34722.1	SEM38901.1	SAMN05414137_101599	SAMN05414137_1265	Hypothetical protein.	Hypothetical protein.	0.772
SEK34722.1	SEM38971.1	SAMN05414137_101599	SAMN05414137_1266	Hypothetical protein.	Hypothetical protein.	0.759
SEM38871.1	SEK24635.1	SAMN05414137_1263	SAMN05414137_101228	TraM recognition site of TraD and TraG.	Xanthomonas XOO_2897-like deaminase.	0.482
SEM38871.1	SEK34722.1	SAMN05414137_1263	SAMN05414137_101599	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.424
SEM38871.1	SEM38890.1	SAMN05414137_1263	SAMN05414137_1264	TraM recognition site of TraD and TraG.	AAA-like domain-containing protein.	0.957
SEM38871.1	SEM38901.1	SAMN05414137_1263	SAMN05414137_1265	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.918
SEM38871.1	SEM38971.1	SAMN05414137_1263	SAMN05414137_1266	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.928
SEM38871.1	SEM38988.1	SAMN05414137_1263	SAMN05414137_1267	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.701
SEM38871.1	SEM66069.1	SAMN05414137_1263	SAMN05414137_14133	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.840
SEM38871.1	SEM66104.1	SAMN05414137_1263	SAMN05414137_14135	TraM recognition site of TraD and TraG.	Hypothetical protein.	0.842
SEM38890.1	SEK24635.1	SAMN05414137_1264	SAMN05414137_101228	AAA-like domain-containing protein.	Xanthomonas XOO_2897-like deaminase.	0.667
SEM38890.1	SEK34722.1	SAMN05414137_1264	SAMN05414137_101599	AAA-like domain-containing protein.	Hypothetical protein.	0.742

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

28

average node degree:

5.09

avg. local clustering coefficient:

0.872

expected number of edges:

14

PPI enrichment p-value:

0.000424

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000271

Polysaccharide biosynthetic process

6 of 59

1.59

2.18

1.58e-06

GO:0009252

Peptidoglycan biosynthetic process

4 of 28

1.74

1.85

7.57e-05

GO:0008360

Regulation of cell shape

4 of 28

1.74

1.85

7.57e-05

GO:0071555

Cell wall organization

4 of 31

1.7

1.81

7.57e-05

GO:0033692

Cellular polysaccharide biosynthetic process

5 of 55

1.54

1.78

2.76e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016881

Acid-amino acid ligase activity

3 of 14

1.92

1.11

0.0068

GO:0016757

Glycosyltransferase activity

4 of 70

1.34

0.86

0.0101

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3065

Mixed, incl. Nucleotide-diphospho-sugar transferases, and O-Antigen nucleotide sugar biosynthesis

7 of 44

1.79

3.17

6.83e-09

CL:2321

Mur ligase, C-terminal, and Glycosyl transferase family 4

4 of 6

2.41

3.16

7.73e-07

CL:3067

Mixed, incl. Nucleotide-diphospho-sugar transferases, and Streptomycin biosynthesis

4 of 31

1.7

1.77

0.00010

CL:3071

Mixed, incl. Polyketide sugar unit biosynthesis, and Glycosyltransferase like family 2

3 of 12

1.98

1.72

0.00037

CL:3073

Glycosyltransferase like family 2, and ABC-2 type transporter

2 of 5

2.19

1.17

0.0065

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

4 of 28

1.74

1.79

0.00011

map01502

Vancomycin resistance

2 of 9

1.93

0.96

0.0146

map01100

Metabolic pathways

10 of 1471

0.42

0.31

0.0129

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0573

Peptidoglycan synthesis

4 of 18

1.93

2.09

4.22e-05

KW-0961

Cell wall biogenesis/degradation

4 of 21

1.87

2.04

4.22e-05

KW-0132

Cell division

4 of 38

1.61

1.62

0.00016

KW-0131

Cell cycle

4 of 38

1.61

1.62

0.00016

KW-0436

Ligase

3 of 84

1.14

0.58

0.0422

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02875

Mur ligase family, glutamate ligase domain

3 of 4

2.46

1.9

0.00029

PF08245

Mur ligase middle domain

3 of 5

2.36

1.88

0.00029

PF01225

Mur ligase family, catalytic domain

2 of 3

2.41

1.03

0.0130

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004101

Mur ligase, C-terminal

3 of 4

2.46

1.69

0.00074

IPR036615

Mur ligase, C-terminal domain superfamily

3 of 5

2.36

1.67

0.00074

IPR036565

Mur-like, catalytic domain superfamily

3 of 5

2.36

1.67

0.00074

IPR013221

Mur ligase, central

3 of 5

2.36

1.67

0.00074

IPR001173

Glycosyltransferase 2-like

3 of 9

2.11

1.57

0.00092

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (20%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About