node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADG881_854 | nfuA | ADG881_854 | ADG881_2956 | [S] COG3139 Uncharacterized protein conserved in bacteria. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.721 |
EDX89217.1 | EDX90623.1 | ADG881_1319 | ADG881_2725 | Aminotransferase, class V superfamily; [E] COG0520 Selenocysteine lyase. | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.682 |
EDX89217.1 | EDX90904.1 | ADG881_1319 | ADG881_3006 | Aminotransferase, class V superfamily; [E] COG0520 Selenocysteine lyase. | Aminotransferase, class V superfamily; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.524 |
EDX89217.1 | nfuA | ADG881_1319 | ADG881_2956 | Aminotransferase, class V superfamily; [E] COG0520 Selenocysteine lyase. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.801 |
EDX89443.1 | EDX89980.1 | ADG881_1545 | ADG881_2082 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.920 |
EDX89443.1 | EDX90776.1 | ADG881_1545 | ADG881_2878 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | 0.966 |
EDX89443.1 | dnaJ | ADG881_1545 | ADG881_2266 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.717 |
EDX89443.1 | nfuA | ADG881_1545 | ADG881_2956 | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.728 |
EDX89980.1 | EDX89443.1 | ADG881_2082 | ADG881_1545 | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.920 |
EDX89980.1 | EDX90623.1 | ADG881_2082 | ADG881_2725 | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.667 |
EDX89980.1 | EDX90904.1 | ADG881_2082 | ADG881_3006 | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Aminotransferase, class V superfamily; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.727 |
EDX89980.1 | nfuA | ADG881_2082 | ADG881_2956 | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.772 |
EDX90595.1 | djlA | ADG881_2697 | ADG881_801 | [O] COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.751 |
EDX90595.1 | nfuA | ADG881_2697 | ADG881_2956 | [O] COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.908 |
EDX90623.1 | EDX89217.1 | ADG881_2725 | ADG881_1319 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Aminotransferase, class V superfamily; [E] COG0520 Selenocysteine lyase. | 0.682 |
EDX90623.1 | EDX89980.1 | ADG881_2725 | ADG881_2082 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Molybdopterin oxidoreductase Fe4S4 domain family; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.667 |
EDX90623.1 | EDX90904.1 | ADG881_2725 | ADG881_3006 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Aminotransferase, class V superfamily; [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes. | 0.781 |
EDX90623.1 | nfuA | ADG881_2725 | ADG881_2956 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.801 |
EDX90776.1 | EDX89443.1 | ADG881_2878 | ADG881_1545 | [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.966 |
EDX90776.1 | nfuA | ADG881_2878 | ADG881_2956 | [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. | HesB-like domain protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.930 |