node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDX90445.1 | EDX90982.1 | ADG881_2547 | ADG881_3084 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.969 |
EDX90445.1 | EDX91073.1 | ADG881_2547 | ADG881_3175 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.967 |
EDX90445.1 | EDX91193.1 | ADG881_2547 | ADG881_3295 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | 0.786 |
EDX90580.1 | EDX91073.1 | ADG881_2682 | ADG881_3175 | Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.559 |
EDX90982.1 | EDX90445.1 | ADG881_3084 | ADG881_2547 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.969 |
EDX90982.1 | EDX91073.1 | ADG881_3084 | ADG881_3175 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.967 |
EDX90982.1 | EDX91193.1 | ADG881_3084 | ADG881_3295 | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | 0.786 |
EDX91073.1 | EDX90445.1 | ADG881_3175 | ADG881_2547 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.967 |
EDX91073.1 | EDX90580.1 | ADG881_3175 | ADG881_2682 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | Thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.559 |
EDX91073.1 | EDX90982.1 | ADG881_3175 | ADG881_3084 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.967 |
EDX91073.1 | EDX91193.1 | ADG881_3175 | ADG881_3295 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | 0.534 |
EDX91073.1 | guaB | ADG881_3175 | ADG881_2407 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.404 |
EDX91073.1 | metG | ADG881_3175 | ADG881_3058 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.477 |
EDX91073.1 | nadK | ADG881_3175 | ADG881_401 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | NAD(+)/NADH kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.652 |
EDX91073.1 | ppk | ADG881_3175 | ADG881_3065 | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. | 0.981 |
EDX91193.1 | EDX90445.1 | ADG881_3295 | ADG881_2547 | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.786 |
EDX91193.1 | EDX90982.1 | ADG881_3295 | ADG881_3084 | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.786 |
EDX91193.1 | EDX91073.1 | ADG881_3295 | ADG881_3175 | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Ppx/GppA phosphatase family; [FP] COG0248 Exopolyphosphatase; Belongs to the GppA/Ppx family. | 0.534 |
EDX91193.1 | guaB | ADG881_3295 | ADG881_2407 | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.658 |
EDX91193.1 | nadK | ADG881_3295 | ADG881_401 | PAS fold family; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain. | NAD(+)/NADH kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.739 |