node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BKCO1_1000641 | BKCO1_200010 | A0A1J9SJR5 | A0A1J9SJV1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxybutyryl-dehydrogenase. | 0.891 |
BKCO1_1000641 | BKCO1_2300059 | A0A1J9SJR5 | A0A1J9R179 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-c-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.974 |
BKCO1_1000641 | BKCO1_2800056 | A0A1J9SJR5 | A0A1J9RM64 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.908 |
BKCO1_1000641 | BKCO1_2900030 | A0A1J9SJR5 | A0A1J9RZ02 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.858 |
BKCO1_1000641 | BKCO1_3700094 | A0A1J9SJR5 | A0A1J9QU33 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.908 |
BKCO1_1000641 | BKCO1_4400035 | A0A1J9SJR5 | A0A1J9QS40 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxymethylglutaryl-lyase. | 0.916 |
BKCO1_1000641 | BKCO1_5800058 | A0A1J9SJR5 | A0A1J9RSU0 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetoacetate-ligase. | 0.849 |
BKCO1_1000641 | BKCO1_720008 | A0A1J9SJR5 | A0A1J9RBH6 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.977 |
BKCO1_1000641 | BKCO1_8000017 | A0A1J9SJR5 | A0A1J9QN10 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.965 |
BKCO1_1170009 | BKCO1_200010 | A0A1J9RM83 | A0A1J9SJV1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxybutyryl-dehydrogenase. | 0.891 |
BKCO1_1170009 | BKCO1_2300059 | A0A1J9RM83 | A0A1J9R179 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-c-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.974 |
BKCO1_1170009 | BKCO1_2800056 | A0A1J9RM83 | A0A1J9RM64 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.908 |
BKCO1_1170009 | BKCO1_2900030 | A0A1J9RM83 | A0A1J9RZ02 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.858 |
BKCO1_1170009 | BKCO1_3700094 | A0A1J9RM83 | A0A1J9QU33 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.908 |
BKCO1_1170009 | BKCO1_4400035 | A0A1J9RM83 | A0A1J9QS40 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxymethylglutaryl-lyase. | 0.916 |
BKCO1_1170009 | BKCO1_5800058 | A0A1J9RM83 | A0A1J9RSU0 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetoacetate-ligase. | 0.849 |
BKCO1_1170009 | BKCO1_720008 | A0A1J9RM83 | A0A1J9RBH6 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.977 |
BKCO1_1170009 | BKCO1_8000017 | A0A1J9RM83 | A0A1J9QN10 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.965 |
BKCO1_200010 | BKCO1_1000641 | A0A1J9SJV1 | A0A1J9SJR5 | 3-hydroxybutyryl-dehydrogenase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.891 |
BKCO1_200010 | BKCO1_1170009 | A0A1J9SJV1 | A0A1J9RM83 | 3-hydroxybutyryl-dehydrogenase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.891 |