node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BKCO1_1000191 | BKCO1_11000126 | A0A1J9SM46 | A0A1J9R8R3 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | 0.647 |
BKCO1_1000191 | BKCO1_460002 | A0A1J9SM46 | A0A1J9RVU8 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Sumo activating enzyme. | 0.647 |
BKCO1_1000191 | BKCO1_6000164 | A0A1J9SM46 | A0A1J9RAY3 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.647 |
BKCO1_1000191 | BKCO1_6500038 | A0A1J9SM46 | A0A1J9RRJ6 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Molybdopterin cofactor biosynthetic protein. | 0.923 |
BKCO1_1000191 | BKCO1_7900036 | A0A1J9SM46 | A0A1J9RPK4 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] | 0.647 |
BKCO1_1000191 | BKCO1_8000045 | A0A1J9SM46 | A0A1J9QKN8 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Nedd8 activating enzyme. | 0.647 |
BKCO1_1000191 | cnxH | A0A1J9SM46 | A0A1J9RBG4 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | 0.990 |
BKCO1_1000191 | uba4 | A0A1J9SM46 | A0A1J9R2F6 | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.774 |
BKCO1_11000126 | BKCO1_1000191 | A0A1J9R8R3 | A0A1J9SM46 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.647 |
BKCO1_11000126 | BKCO1_6000164 | A0A1J9R8R3 | A0A1J9RAY3 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.402 |
BKCO1_11000126 | BKCO1_6500038 | A0A1J9R8R3 | A0A1J9RRJ6 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Molybdopterin cofactor biosynthetic protein. | 0.686 |
BKCO1_11000126 | BKCO1_8000045 | A0A1J9R8R3 | A0A1J9QKN8 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Nedd8 activating enzyme. | 0.999 |
BKCO1_11000126 | cnxH | A0A1J9R8R3 | A0A1J9RBG4 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | 0.889 |
BKCO1_11000126 | uba4 | A0A1J9R8R3 | A0A1J9R2F6 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.422 |
BKCO1_2400095 | cnxH | A0A1J9R0Y3 | A0A1J9RBG4 | Saga complex component. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | 0.921 |
BKCO1_460002 | BKCO1_1000191 | A0A1J9RVU8 | A0A1J9SM46 | Sumo activating enzyme. | Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. | 0.647 |
BKCO1_460002 | BKCO1_6000164 | A0A1J9RVU8 | A0A1J9RAY3 | Sumo activating enzyme. | Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. | 0.998 |
BKCO1_460002 | BKCO1_6500038 | A0A1J9RVU8 | A0A1J9RRJ6 | Sumo activating enzyme. | Molybdopterin cofactor biosynthetic protein. | 0.686 |
BKCO1_460002 | BKCO1_8000045 | A0A1J9RVU8 | A0A1J9QKN8 | Sumo activating enzyme. | Nedd8 activating enzyme. | 0.461 |
BKCO1_460002 | cnxH | A0A1J9RVU8 | A0A1J9RBG4 | Sumo activating enzyme. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. | 0.889 |