STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB39988.1Signal transduction histidine kinase. (750 aa)    
Predicted Functional Partners:
SFA98262.1
PAS domain S-box-containing protein.
  
 0.999
SFB16133.1
Response regulator receiver domain-containing protein.
  
 0.999
SFB33969.1
Response regulator receiver domain-containing protein.
  
 0.999
SFB56914.1
TolB amino-terminal domain-containing protein.
  
 0.999
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.997
SFB43933.1
DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains.
  
 0.996
SFB41413.1
PAS domain S-box-containing protein.
 
 0.978
SFB26604.1
Signal transduction histidine kinase.
  
 0.971
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 0.967
SFA85967.1
Curved DNA-binding protein.
  
 0.967
Your Current Organism:
Algoriphagus aquimarinus
NCBI taxonomy Id: 237018
Other names: A. aquimarinus, Algoriphagus aquimarinus Nedashkovskaya et al. 2004, CCUG 47101, DSM 23399, KMM 3958, LMG 21971, LMG:21971
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