STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB45451.1CarboxypepD_reg-like domain-containing protein. (371 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.608
SFB48708.1
Tricorn protease; Degrades oligopeptides; Belongs to the peptidase S41B family.
  
     0.590
SFB27189.1
Protein of unknown function.
  
     0.551
SFB12197.1
Protein of unknown function.
  
     0.502
SFB37139.1
TonB family C-terminal domain-containing protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
   0.498
SFA93011.1
Hypothetical protein.
  
 
   0.497
SFB09761.1
CarboxypepD_reg-like domain-containing protein.
  
 
  
0.487
SFB61417.1
Protein of unknown function.
  
     0.481
SFA80185.1
Transglutaminase-like superfamily protein.
  
     0.479
SFA80203.1
Protein of unknown function.
  
     0.474
Your Current Organism:
Algoriphagus aquimarinus
NCBI taxonomy Id: 237018
Other names: A. aquimarinus, Algoriphagus aquimarinus Nedashkovskaya et al. 2004, CCUG 47101, DSM 23399, KMM 3958, LMG 21971, LMG:21971
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.