node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFA80499.1 | SFB57930.1 | SAMN04489723_101408 | SAMN04489723_1236 | Glutamate synthase (NADH) large subunit. | DNA-binding transcriptional regulator, MerR family. | 0.846 |
SFA80499.1 | icmF | SAMN04489723_101408 | SAMN04489723_12145 | Glutamate synthase (NADH) large subunit. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.866 |
SFA80499.1 | mdh | SAMN04489723_101408 | SAMN04489723_12048 | Glutamate synthase (NADH) large subunit. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.892 |
SFA80499.1 | pckA | SAMN04489723_101408 | SAMN04489723_108131 | Glutamate synthase (NADH) large subunit. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.877 |
SFA80499.1 | sucC | SAMN04489723_101408 | SAMN04489723_10831 | Glutamate synthase (NADH) large subunit. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.887 |
SFA80499.1 | sucD | SAMN04489723_101408 | SAMN04489723_10533 | Glutamate synthase (NADH) large subunit. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.894 |
SFB18725.1 | SFB18752.1 | SAMN04489723_105164 | SAMN04489723_105165 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Heterodimeric methylmalonyl-CoA mutase small subunit. | 0.999 |
SFB18725.1 | SFB40897.1 | SAMN04489723_105164 | SAMN04489723_10985 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 4-hydroxyphenylpyruvate dioxygenase. | 0.876 |
SFB18725.1 | SFB56799.1 | SAMN04489723_105164 | SAMN04489723_12146 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Acyl-CoA hydrolase. | 0.956 |
SFB18725.1 | SFB57930.1 | SAMN04489723_105164 | SAMN04489723_1236 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | DNA-binding transcriptional regulator, MerR family. | 0.869 |
SFB18725.1 | icmF | SAMN04489723_105164 | SAMN04489723_12145 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |
SFB18725.1 | mdh | SAMN04489723_105164 | SAMN04489723_12048 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.859 |
SFB18725.1 | pckA | SAMN04489723_105164 | SAMN04489723_108131 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.855 |
SFB18725.1 | sucC | SAMN04489723_105164 | SAMN04489723_10831 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.851 |
SFB18725.1 | sucD | SAMN04489723_105164 | SAMN04489723_10533 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.870 |
SFB18752.1 | SFB18725.1 | SAMN04489723_105165 | SAMN04489723_105164 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.999 |
SFB18752.1 | SFB40897.1 | SAMN04489723_105165 | SAMN04489723_10985 | Heterodimeric methylmalonyl-CoA mutase small subunit. | 4-hydroxyphenylpyruvate dioxygenase. | 0.876 |
SFB18752.1 | SFB56799.1 | SAMN04489723_105165 | SAMN04489723_12146 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Acyl-CoA hydrolase. | 0.915 |
SFB18752.1 | SFB57930.1 | SAMN04489723_105165 | SAMN04489723_1236 | Heterodimeric methylmalonyl-CoA mutase small subunit. | DNA-binding transcriptional regulator, MerR family. | 0.869 |
SFB18752.1 | icmF | SAMN04489723_105165 | SAMN04489723_12145 | Heterodimeric methylmalonyl-CoA mutase small subunit. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |