node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM85521.1 | SDN23223.1 | SAMN05216498_0803 | SAMN05216498_1794 | Fumarate reductase (CoM/CoB) subunit A. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 0.965 |
SDM85521.1 | SDN23297.1 | SAMN05216498_0803 | SAMN05216498_1796 | Fumarate reductase (CoM/CoB) subunit A. | Succinate dehydrogenase / fumarate reductase cytochrome b subunit. | 0.969 |
SDM85521.1 | fumC | SAMN05216498_0803 | SAMN05216498_0110 | Fumarate reductase (CoM/CoB) subunit A. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.835 |
SDM85521.1 | mdh | SAMN05216498_0803 | SAMN05216498_1839 | Fumarate reductase (CoM/CoB) subunit A. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.686 |
SDM85521.1 | odhA | SAMN05216498_0803 | SAMN05216498_0072 | Fumarate reductase (CoM/CoB) subunit A. | 2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.813 |
SDM85521.1 | sucC | SAMN05216498_0803 | SAMN05216498_1185 | Fumarate reductase (CoM/CoB) subunit A. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.868 |
SDM85521.1 | sucD | SAMN05216498_0803 | SAMN05216498_1184 | Fumarate reductase (CoM/CoB) subunit A. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.874 |
SDN23223.1 | SDM85521.1 | SAMN05216498_1794 | SAMN05216498_0803 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Fumarate reductase (CoM/CoB) subunit A. | 0.965 |
SDN23223.1 | SDN23266.1 | SAMN05216498_1794 | SAMN05216498_1795 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Succinate dehydrogenase / fumarate reductase flavoprotein subunit. | 0.997 |
SDN23223.1 | SDN23297.1 | SAMN05216498_1794 | SAMN05216498_1796 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Succinate dehydrogenase / fumarate reductase cytochrome b subunit. | 0.999 |
SDN23223.1 | SDN24920.1 | SAMN05216498_1794 | SAMN05216498_1850 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Malate dehydrogenase (oxaloacetate-decarboxylating). | 0.600 |
SDN23223.1 | fumC | SAMN05216498_1794 | SAMN05216498_0110 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.817 |
SDN23223.1 | mdh | SAMN05216498_1794 | SAMN05216498_1839 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.853 |
SDN23223.1 | odhA | SAMN05216498_1794 | SAMN05216498_0072 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 2-oxoglutarate dehydrogenase E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.809 |
SDN23223.1 | sucC | SAMN05216498_1794 | SAMN05216498_1185 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.936 |
SDN23223.1 | sucD | SAMN05216498_1794 | SAMN05216498_1184 | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.957 |
SDN23266.1 | SDN23223.1 | SAMN05216498_1795 | SAMN05216498_1794 | Succinate dehydrogenase / fumarate reductase flavoprotein subunit. | Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. | 0.997 |
SDN23266.1 | SDN23297.1 | SAMN05216498_1795 | SAMN05216498_1796 | Succinate dehydrogenase / fumarate reductase flavoprotein subunit. | Succinate dehydrogenase / fumarate reductase cytochrome b subunit. | 0.998 |
SDN23266.1 | fumC | SAMN05216498_1795 | SAMN05216498_0110 | Succinate dehydrogenase / fumarate reductase flavoprotein subunit. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.928 |
SDN23266.1 | mdh | SAMN05216498_1795 | SAMN05216498_1839 | Succinate dehydrogenase / fumarate reductase flavoprotein subunit. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.724 |