STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN03111.1L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa)    
Predicted Functional Partners:
SDN03091.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.788
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
    0.764
SDN38887.1
Threonine dehydratase.
  
 
 0.660
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.614
SDN07812.1
Homoserine dehydrogenase.
   
 
  0.598
SDN89115.1
Serine O-acetyltransferase.
     
 0.597
fapR
Acyl-coenzyme A thioesterase PaaI, contains HGG motif; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
       0.592
SDN97944.1
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
  0.576
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.569
Your Current Organism:
Tenuibacillus multivorans
NCBI taxonomy Id: 237069
Other names: AS 1.3442, CGMCC 1.3442, NBRC 100370, T. multivorans, Tenuibacillus multivorans Ren and Zhou 2005, cf. Filobacillus sp. 1, strain 28-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.