STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addADNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase. (1239 aa)    
Predicted Functional Partners:
addB
DNA helicase/exodeoxyribonuclease V, subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.
 
 
 0.999
recD2
Exodeoxyribonuclease V alpha subunit; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.897
SDN27536.1
Uncharacterized membrane protein YdjX, TVP38/TMEM64 family, SNARE-associated domain.
       0.800
SDN62442.1
ATP-dependent DNA helicase RecQ.
    
 0.708
SDN18905.1
tRNA (adenine22-N1)-methyltransferase.
 
     0.695
SDN76174.1
DNA helicase-2 / ATP-dependent DNA helicase PcrA.
 
 
0.666
sbcD
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.619
SDM84640.1
Superfamily I DNA and RNA helicases.
  
 
 0.592
recA
Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.562
ligA
DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
  
 
 0.535
Your Current Organism:
Tenuibacillus multivorans
NCBI taxonomy Id: 237069
Other names: AS 1.3442, CGMCC 1.3442, NBRC 100370, T. multivorans, Tenuibacillus multivorans Ren and Zhou 2005, cf. Filobacillus sp. 1, strain 28-1
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