STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN47910.1hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (418 aa)    
Predicted Functional Partners:
SDN49661.1
3-oxo-5,6-didehydrosuberyl-CoA/3-oxoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.909
SDN67385.1
acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.877
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.873
SDN47978.1
Tripartite tricarboxylate transporter TctA family protein.
 
     0.793
SDN26263.1
Protein of unknown function; Belongs to the UPF0311 family.
   
  
 0.791
SDM82504.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.779
SDM90007.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.683
SDN51112.1
Hypothetical protein.
 
  
  0.677
SDN47945.1
Hypothetical protein.
       0.675
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.671
Your Current Organism:
Tenuibacillus multivorans
NCBI taxonomy Id: 237069
Other names: AS 1.3442, CGMCC 1.3442, NBRC 100370, T. multivorans, Tenuibacillus multivorans Ren and Zhou 2005, cf. Filobacillus sp. 1, strain 28-1
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