STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDN63372.1Stage II sporulation protein AA (anti-sigma F factor antagonist); Belongs to the anti-sigma-factor antagonist family. (117 aa)    
Predicted Functional Partners:
spoIIAB
Stage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 0.999
SDN63310.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.947
rsbW
Serine/threonine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 
 0.878
SDN42848.1
RNA polymerase sigma-B factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.878
SDN63204.1
Stage V sporulation protein AC.
 
   
 0.777
SDN63184.1
Stage V sporulation protein AD.
 
   
 0.756
SDN63152.1
Stage V sporulation protein AE.
 
     0.726
SDN61815.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.681
SDN63119.1
Stage V sporulation protein AF.
 
     0.626
SDN42710.1
Serine/threonine-protein kinase RsbT.
  
 
 0.625
Your Current Organism:
Tenuibacillus multivorans
NCBI taxonomy Id: 237069
Other names: AS 1.3442, CGMCC 1.3442, NBRC 100370, T. multivorans, Tenuibacillus multivorans Ren and Zhou 2005, cf. Filobacillus sp. 1, strain 28-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.