STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpxThiol peroxidase, atypical 2-Cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (165 aa)    
Predicted Functional Partners:
SDO60647.1
Uncharacterized conserved protein YndB, AHSA1/START domain.
       0.588
SDO49344.1
Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.582
SDO88476.1
Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.582
SDO66152.1
Peroxiredoxin (alkyl hydroperoxide reductase subunit C).
  
  
 0.566
SDO60606.1
Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family.
       0.525
gcvP
Glycine dehydrogenase; Belongs to the GcvP family.
       0.521
SDO60663.1
DnaJ domain-containing protein.
   
   0.516
SDO28834.1
NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.475
msrA-2
Peptide methionine sulfoxide reductase msrA/msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.465
SDO92616.1
Iron (metal) dependent repressor, DtxR family.
  
  
 0.425
Your Current Organism:
Cloacibacterium normanense
NCBI taxonomy Id: 237258
Other names: ATCC BAA-825, C. normanense, CCUG 46293, CIP 108613, Cloacibacterium normanense Allen et al. 2006, Cloacibacterium sp. IMET F, DSM 15886, cf. Bergeyella sp. CCUG 46293, strain NRS1
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