STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTR2Low-affinity Cu transporter. (162 aa)    
Predicted Functional Partners:
CCC2
Cu(2+)-transporting P-type ATPase.
    
 
 0.903
COX17
Copper metallochaperone.
   
  
 0.871
CFL1
Ferric/cupric reductase transmembrane component 1; Ferric reductase responsible for reducing extracellular iron and copper prior to import. Catalyzes the reductive uptake of Fe(3+)- salts and Fe(3+) bound to catecholate or hydroxamate siderophores. Fe(3+) is reduced to Fe(2+), which then dissociates from the siderophore and can be imported by the high-affinity Fe(2+) transport complex in the plasma membrane. Also participates in Cu(2+) reduction and Cu(+) uptake (By similarity). Involved in maintenance of cell wall integrity (CWI), mitochondrial function, and interaction between the pa [...]
      
 0.700
ATX1
Copper metallochaperone.
      
 0.661
RGA2
Rga2p.
   
  
 0.634
CUP2
Cup2p.
      
 0.627
COX11
Cox11p.
      
 0.596
CTR1
Copper transport protein CTR1; Required for high affinity copper (probably reduced Cu I) transport into the cell.
    
 
 0.576
FRE7
Fre7p.
      
 0.571
ZRC1
Zn(2+) transporter.
      
 0.522
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
Server load: low (16%) [HD]