STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECM21Ecm21p. (728 aa)    
Predicted Functional Partners:
MNN23
Alpha-1,2-mannosyltransferase MNN23; Alpha-1,2-mannosyltransferase required for cell wall integrity. Responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides. Addition of alpha-1,2-mannose is required for stabilization of the alpha-1,6-mannose backbone and hence regulates mannan fibril length; and is important for both immune recognition and virulence; Belongs to the MNN1/MNT family.
      
 0.674
CaO19.5282
Uncharacterized protein.
   
    0.664
NMD4
Nonsense-mediated decay protein 4; Involved in nonsense-mediated decay of mRNAs containing premature stop codons.
      
 0.620
NCP1
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
      
 0.619
RSP5
E3 ubiquitin-protein ligase.
   
 
 0.615
ASR1
Asr1p.
   
 
 0.593
CDR3
Cdr3p.
   
  
 0.558
CaO19.449
Uncharacterized protein.
   
    0.539
STB3
Stb3p.
   
    0.529
ERO1
ER oxidoreductin.
   
  
 0.525
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.