STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CaO19.2257Uncharacterized protein. (367 aa)    
Predicted Functional Partners:
SEC61
Protein transport protein SEC61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity).
   
 
 0.832
RPL5
Ribosomal 60S subunit protein L5.
   
   0.789
RPL20B
60S ribosomal protein L20; Belongs to the eukaryotic ribosomal protein eL20 family.
   
   0.762
RPL21A
Ribosomal 60S subunit protein L21A.
   
   0.747
A0A1D8PRY9
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
   0.747
RPL3
Ribosomal 60S subunit protein L3; Belongs to the universal ribosomal protein uL3 family.
   
   0.745
RPL11
Ribosomal 60S subunit protein L11B; Belongs to the universal ribosomal protein uL5 family.
   
   0.741
RPL38
Ribosomal 60S subunit protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
   
 
 0.739
A0A1D8PKK1
Translocon subunit.
   
   0.738
RPL16A
Ribosomal 60S subunit protein L16A; Belongs to the universal ribosomal protein uL13 family.
   
   0.736
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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