STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BEM1Phosphatidylinositol-3-phosphate-binding protein. (632 aa)    
Predicted Functional Partners:
CDC24
Rho family guanine nucleotide exchange factor.
   
 0.999
CDC42
Cell division control protein 42 homolog; Involved in hyphal formation, virulence, morphogenesis; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
   
 0.999
CST20
Serine/threonine-protein kinase CST20; MAP4K component of the MAPK pathway required for the mating pheromone response, and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Required for hyphal formation and virulence; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    
 0.996
CLA4
Serine/threonine-protein kinase CLA4; Ser/Thr kinase required for wild-type filamentous growth, chlamydospore formation, and virulence in mouse systemic infection. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
   
 0.986
RGA2
Rga2p.
   
 
 0.902
SEC15
Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    
 
 0.884
BOI2
Boi2p.
   
 
 0.861
RSR1
Ras family GTPase.
   
 0.854
RAC1
Rho family GTPase.
   
 0.846
EXO70
Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst (By similarity). Belongs to the EXO70 family.
    
 
 0.844
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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