STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCE1CAAX prenyl protease. (281 aa)    
Predicted Functional Partners:
STE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
   
 0.997
RAM2
Bifunctional protein farnesyltransferase/protein geranylgeranyltransferase.
     
 0.996
RAM1
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
    
 0.990
CaO19.119
Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
   
 0.945
CaO19.120
Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
   
 0.944
AXL1
Axl1p.
      
 0.873
STE23
Metalloendopeptidase.
   
  
 0.727
RAS1
Ras-like protein 1; Required for the regulation of both a MAP kinase signaling pathway and a cAMP signaling pathway. The activation of these pathways contributes to the pathogenicity of the cells through the induction of the morphological transition from the yeast to the polarized filamentous form (By similarity).
    
 0.688
RSR1
Ras family GTPase.
    
 0.659
CDC43
Protein geranylgeranyltransferase type I subunit.
      
 0.614
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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