STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFB3TFIIH/NER complex subunit. (360 aa)    
Predicted Functional Partners:
CaO19.1457
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
   
 0.999
CaO19.5297
TFIIH/NER complex subunit.
   
 0.999
CaO19.4194
TFIIH/NER complex subunit.
   
 0.999
RAD3
TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit.
    
 0.999
CaO19.2857
TFIIH/NER complex ATPase/helicase subunit.
   
 0.999
CaO19.5846
RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.999
CaO19.4542
TFIIH complex kinase subunit; Belongs to the cyclin family.
   
 0.999
KIN28
TFIIH complex serine/threonine-protein kinase subunit; Belongs to the protein kinase superfamily.
 
 
 0.999
CaO19.4882
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
   
 0.997
TFA1
Transcription factor TFIIE subunit.
    
 0.996
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.