STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSR1Ras family GTPase. (248 aa)    
Predicted Functional Partners:
BUD2
GTPase activating protein BUD2; GTPase activating protein (GAP) for RSR1 which is involved in the polarization of yeast and hyphal cells. Directs the site of new daughter cell growth in yeast and hyphal cells. Important for hyphae to maintain linear growth and necessary for hyphal responses to directional cues in the environment (tropisms). Required for correct localization of the septin rings and stabilization of the polarisome at hyphal tips. Involved in cell adhesion.
   
 0.982
CDC24
Rho family guanine nucleotide exchange factor.
   
 0.948
RGA2
Rga2p.
    
 0.946
BUD5
Ras family guanine nucleotide exchange factor.
    
 0.937
IRA2
Ras GTPase activating protein.
   
 0.878
BEM1
Phosphatidylinositol-3-phosphate-binding protein.
   
 0.854
CaO19.5271
Uncharacterized protein.
   
 0.760
BMH1
14-3-3 protein homolog; Belongs to the 14-3-3 family.
   
 0.729
RAM1
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
    
 0.727
LRG1
Lrg1p.
   
 0.725
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.