STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEM15-aminolevulinate synthase, mitochondrial; Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (564 aa)    
Predicted Functional Partners:
HEM2
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
    
 0.980
HEM14
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
     
 0.934
GCV2
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.926
SHM1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.919
SHM2
Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine; Belongs to the SHMT family.
  
 
 0.919
GLY1
Gly1p.
   
 
 0.919
CaO19.6305
Threonine aldolase.
     
 0.915
DAO1
Dao1p.
  
 
 0.907
DAO2
Dao2p.
  
 
 0.907
IFG3
Ifg3p.
  
 
 0.907
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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