node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDC20 | CDC28 | A0A1D8PPK6 | P43063 | Ubiquitin-protein transferase activating protein. | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | 0.936 |
CDC20 | CLN3 | A0A1D8PPK6 | Q5A1N6 | Ubiquitin-protein transferase activating protein. | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | 0.818 |
CDC20 | HGC1 | A0A1D8PPK6 | Q5ABE2 | Ubiquitin-protein transferase activating protein. | Hypha-specific G1 cyclin-related protein 1; Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis and opaque cells filamentous growth, and required for both conventional and pheromone-stimulated biofilm formation. Required to maintain hyphal tip localization of actin and SPA2. Regulates the CDC28 kinase during hyphal growth. The CDC28-HGC1 complex phosphorylates and prevents RGA2 from localizing to hyphal tips, leading to localized CDC42 activation for hyphal extension. The CDC28-HGC1 complex also phosphorylates SEC2 and maintains CDC11 phosphorylation throug [...] | 0.744 |
CDC20 | NSP1 | A0A1D8PPK6 | A0A1D8PGV7 | Ubiquitin-protein transferase activating protein. | FG-nucleoporin. | 0.629 |
CDC20 | PHO85 | A0A1D8PPK6 | A0A1D8PDA6 | Ubiquitin-protein transferase activating protein. | Cyclin-dependent serine/threonine-protein kinase; Belongs to the protein kinase superfamily. | 0.828 |
CDC20 | SWI6 | A0A1D8PPK6 | A0A1D8PED2 | Ubiquitin-protein transferase activating protein. | Transcriptional regulator. | 0.493 |
CDC28 | CDC20 | P43063 | A0A1D8PPK6 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | Ubiquitin-protein transferase activating protein. | 0.936 |
CDC28 | CLN3 | P43063 | Q5A1N6 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | 0.999 |
CDC28 | HGC1 | P43063 | Q5ABE2 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | Hypha-specific G1 cyclin-related protein 1; Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis and opaque cells filamentous growth, and required for both conventional and pheromone-stimulated biofilm formation. Required to maintain hyphal tip localization of actin and SPA2. Regulates the CDC28 kinase during hyphal growth. The CDC28-HGC1 complex phosphorylates and prevents RGA2 from localizing to hyphal tips, leading to localized CDC42 activation for hyphal extension. The CDC28-HGC1 complex also phosphorylates SEC2 and maintains CDC11 phosphorylation throug [...] | 0.999 |
CDC28 | MBP1 | P43063 | A0A1D8PJV0 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | Transcription factor. | 0.504 |
CDC28 | NSP1 | P43063 | A0A1D8PGV7 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | FG-nucleoporin. | 0.971 |
CDC28 | SWI4 | P43063 | A0A1D8PCM9 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | SBF complex DNA-binding subunit. | 0.971 |
CDC28 | SWI6 | P43063 | A0A1D8PED2 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | Transcriptional regulator. | 0.978 |
CLN3 | CDC20 | Q5A1N6 | A0A1D8PPK6 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Ubiquitin-protein transferase activating protein. | 0.818 |
CLN3 | CDC28 | Q5A1N6 | P43063 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] | 0.999 |
CLN3 | HGC1 | Q5A1N6 | Q5ABE2 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Hypha-specific G1 cyclin-related protein 1; Hypha-specific G1 cyclin-related protein involved in regulation of morphogenesis and opaque cells filamentous growth, and required for both conventional and pheromone-stimulated biofilm formation. Required to maintain hyphal tip localization of actin and SPA2. Regulates the CDC28 kinase during hyphal growth. The CDC28-HGC1 complex phosphorylates and prevents RGA2 from localizing to hyphal tips, leading to localized CDC42 activation for hyphal extension. The CDC28-HGC1 complex also phosphorylates SEC2 and maintains CDC11 phosphorylation throug [...] | 0.871 |
CLN3 | MBP1 | Q5A1N6 | A0A1D8PJV0 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Transcription factor. | 0.988 |
CLN3 | NSP1 | Q5A1N6 | A0A1D8PGV7 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | FG-nucleoporin. | 0.974 |
CLN3 | PHO85 | Q5A1N6 | A0A1D8PDA6 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Cyclin-dependent serine/threonine-protein kinase; Belongs to the protein kinase superfamily. | 0.931 |
CLN3 | RME1 | Q5A1N6 | Q59WD1 | G1/S-specific cyclin CLN3; G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition. CLN3 may be an upstream activator of the G1 cyclins which directly catalyze start. Required for budding and for cell cycle progression and morphogenesis in environment-induced hyphae. Degradation is mediated by GRR1. Through binding to CDC28, controls the phosphorylation of SLA1 which regulates cortical actin patch dynamics. | Rme1p. | 0.956 |