node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALS3 | HYR4 | Q59L12 | Q5A849 | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.448 |
ALS3 | RBT1 | Q59L12 | Q59TP1 | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | 0.905 |
ALS3 | YWP1 | Q59L12 | Q59Y31 | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | 0.799 |
CaO19.2200 | CaO19.6449 | Q5A2K5 | Q5A314 | L-type lectin-like domain-containing protein. | Uncharacterized protein. | 0.478 |
CaO19.2200 | HYR4 | Q5A2K5 | Q5A849 | L-type lectin-like domain-containing protein. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.454 |
CaO19.6449 | CaO19.2200 | Q5A314 | Q5A2K5 | Uncharacterized protein. | L-type lectin-like domain-containing protein. | 0.478 |
CaO19.6449 | HYR4 | Q5A314 | Q5A849 | Uncharacterized protein. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.482 |
HYR4 | ALS3 | Q5A849 | Q59L12 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | 0.448 |
HYR4 | CaO19.2200 | Q5A849 | Q5A2K5 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | L-type lectin-like domain-containing protein. | 0.454 |
HYR4 | CaO19.6449 | Q5A849 | Q5A314 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | Uncharacterized protein. | 0.482 |
HYR4 | RBT1 | Q5A849 | Q59TP1 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | 0.454 |
HYR4 | RIM9 | Q5A849 | Q59WV0 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | pH-response regulator protein palI/RIM9; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH; Belongs to the palI/RIM9 family. | 0.470 |
HYR4 | YWP1 | Q5A849 | Q59Y31 | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | 0.499 |
RBT1 | ALS3 | Q59TP1 | Q59L12 | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | 0.905 |
RBT1 | HYR4 | Q59TP1 | Q5A849 | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.454 |
RBT1 | YWP1 | Q59TP1 | Q59Y31 | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | 0.531 |
RIM9 | HYR4 | Q59WV0 | Q5A849 | pH-response regulator protein palI/RIM9; Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH; Belongs to the palI/RIM9 family. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.470 |
YWP1 | ALS3 | Q59Y31 | Q59L12 | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | Agglutinin-like protein 3; Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells. During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys. Belongs to the ALS family. | 0.799 |
YWP1 | HYR4 | Q59Y31 | Q5A849 | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | Hyphally regulated cell wall protein 4; GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence; Belongs to the HYR1/IFF family. | 0.499 |
YWP1 | RBT1 | Q59Y31 | Q59TP1 | Yeast-form wall Protein 1; Cell wall protein which plays an anti-adhesive role and promotes dispersal of yeast forms, which allows the organism to seek new sites for colonization. | Cell wall protein RTB1; GPI-anchored cell wall protein required for mating efficiency, biofilm formation, and virulence. Involved in normal disseminated infection, but not in intestinal colonization. | 0.531 |