STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNA1Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (149 aa)    
Predicted Functional Partners:
AGM1
Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.
   
 
 0.994
GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).
  
 0.993
NAG1
Glucosamine-6-phosphate isomerase.
   
 
 0.982
DAC1
N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.
     
 0.948
HXK1
N-acetylglucosamine kinase 1; Component of the N-acetylglucosamine catabolic cascade that phosphorylates N-acetylglucosamine (GlcNAc), and allows the unique ability to utilise GlcNAc as carbon source. Converts GlcNAc to GlcNAc- 6-P. Also able to phosphorylate glucose, glucosamine (GlcN), and mannose. Galactose, fructose, N-acetylmannosamine (ManNAc), mannosamine (ManN), galactosamine (GalN), and N-acetylgalactosamine (GalNAc) are not phosphorylated by HXK1. GlcNAc metabolism is closely associated with virulence and morphogenesis, and is involved in the cell wall synthesis. Acts both as [...]
   
 0.944
UAP1
UDP-N-acetylglucosamine diphosphorylase.
   
 
 0.936
GLK1
Phosphotransferase.
   
 0.933
HXK2
Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate.
   
 0.930
GLK4
Phosphotransferase.
   
 0.922
CaO19.6847
tRNA (Uracil) methyltransferase.
 
      0.816
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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