STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOM2Aspartate-semialdehyde dehydrogenase. (365 aa)    
Predicted Functional Partners:
HOM3
Aspartokinase.
 
 0.999
HOM6
Homoserine dehydrogenase.
  
 0.997
THR4
Threonine synthase.
  
 
 0.967
ARG5,6
Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family.
 
  
 0.940
THR1
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.934
TRP5
Tryptophan synthase.
  
  
 0.919
HIS4
Histidine biosynthesis trifunctional protein.
  
  
 0.915
ARO2
Chorismate synthase.
  
  
 0.890
ILV3
Dihydroxy-acid dehydratase.
  
  
 0.810
ARG1
Argininosuccinate synthase.
  
  
 0.786
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.