STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCM1Hcm1p. (579 aa)    
Predicted Functional Partners:
ABD1
mRNA cap guanine-N7 methyltransferase; Responsible for methylating the 5'-cap structure of mRNAs. Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
   
  
 0.867
CDC5
Serine/threonine-protein kinase.
   
 0.807
YOX1
Yox1p.
   
 0.784
MCD1
Kleisin alpha.
   
  
 0.763
CDC28
Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...]
   
 0.753
GIN1
Chromatin-modulating protein.
   
  
 0.729
MIH1
Putative tyrosine protein phosphatase.
   
 0.696
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
   0.694
FKH2
Fork-head transcriptional regulator 2; Transcription factor required for the morphogenesis of true hyphal as well as yeast cells. Contributes to virulence.
  
 
0.691
CET1
mRNA-capping enzyme subunit beta; First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
    
 
 0.685
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.