node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APQ11453.1 | APQ11465.1 | BJP27_08025 | BJP27_08085 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.668 |
APQ11453.1 | APQ11466.1 | BJP27_08025 | BJP27_08090 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.860 |
APQ11453.1 | APQ11469.1 | BJP27_08025 | BJP27_08105 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.811 |
APQ11453.1 | APQ11470.1 | BJP27_08025 | BJP27_08110 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.990 |
APQ11453.1 | APQ11472.1 | BJP27_08025 | BJP27_08120 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.790 |
APQ11453.1 | cyaY | BJP27_08025 | BJP27_15675 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.877 |
APQ11453.1 | hscA | BJP27_08025 | BJP27_08095 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.736 |
APQ11453.1 | hscB | BJP27_08025 | BJP27_08100 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.848 |
APQ11453.1 | iscS | BJP27_08025 | BJP27_08115 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.903 |
APQ11453.1 | nfuA | BJP27_08025 | BJP27_02470 | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.904 |
APQ11465.1 | APQ11453.1 | BJP27_08085 | BJP27_08025 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.668 |
APQ11465.1 | APQ11466.1 | BJP27_08085 | BJP27_08090 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ferredoxin, 2Fe-2S type, ISC system; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
APQ11465.1 | APQ11469.1 | BJP27_08085 | BJP27_08105 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.910 |
APQ11465.1 | APQ11470.1 | BJP27_08085 | BJP27_08110 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.953 |
APQ11465.1 | APQ11472.1 | BJP27_08085 | BJP27_08120 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S cluster assembly transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. | 0.682 |
APQ11465.1 | cyaY | BJP27_08085 | BJP27_15675 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.721 |
APQ11465.1 | hscA | BJP27_08085 | BJP27_08095 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.954 |
APQ11465.1 | hscB | BJP27_08085 | BJP27_08100 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.972 |
APQ11465.1 | iscS | BJP27_08085 | BJP27_08115 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | IscS subfamily cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.922 |
APQ11465.1 | nfuA | BJP27_08085 | BJP27_02470 | Fe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.613 |