node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | TSD2 | A0A0D1DNS0 | Q99107 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | 0.999 |
MCM7 | UMAG_00366 | A0A0D1DNS0 | A0A0D1E7U1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | UMAG_01445 | A0A0D1DNS0 | A0A0D1E288 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | UMAG_01646 | A0A0D1DNS0 | A0A0D1E418 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | UMAG_01679 | A0A0D1DNS0 | A0A0D1CVV6 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase. | 0.999 |
MCM7 | UMAG_02543 | A0A0D1DNS0 | A0A0D1C6C8 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.997 |
MCM7 | UMAG_03496 | A0A0D1DNS0 | A0A0D1E143 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Chromosome 9, whole genome shotgun sequence. | 0.999 |
MCM7 | UMAG_05064 | A0A0D1DNS0 | A0A0D1CK07 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | UMAG_06087 | A0A0D1DNS0 | A0A0D1BVB2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.998 |
MCM7 | UMAG_10237 | A0A0D1DNS0 | A0A0D1CED2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Protein kinase domain-containing protein. | 0.997 |
TSD2 | MCM7 | Q99107 | A0A0D1DNS0 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
TSD2 | UMAG_00366 | Q99107 | A0A0D1E7U1 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA helicase; Belongs to the MCM family. | 0.999 |
TSD2 | UMAG_01445 | Q99107 | A0A0D1E288 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA helicase; Belongs to the MCM family. | 0.999 |
TSD2 | UMAG_01646 | Q99107 | A0A0D1E418 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA helicase; Belongs to the MCM family. | 0.999 |
TSD2 | UMAG_01679 | Q99107 | A0A0D1CVV6 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA helicase. | 0.999 |
TSD2 | UMAG_02543 | Q99107 | A0A0D1C6C8 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | Uncharacterized protein. | 0.944 |
TSD2 | UMAG_03496 | Q99107 | A0A0D1E143 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | Chromosome 9, whole genome shotgun sequence. | 0.932 |
TSD2 | UMAG_05064 | Q99107 | A0A0D1CK07 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | DNA helicase; Belongs to the MCM family. | 0.999 |
TSD2 | UMAG_06087 | Q99107 | A0A0D1BVB2 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.977 |
TSD2 | UMAG_10237 | Q99107 | A0A0D1CED2 | Protein TSD2; Temperature-sensitive protein required for DNA synthesis. May be a transcription factor that regulates the level or influences the stability of DNA polymerases or auxiliary proteins. | Protein kinase domain-containing protein. | 0.892 |