Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFA72201.12-oxoisovalerate dehydrogenase E1 component beta subunit. (327 aa)    
Predicted Functional Partners:
SFA72183.1
2-oxoisovalerate dehydrogenase E1 component alpha subunit.
 0.999
SFA72218.1
2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase).
 0.998
SFB00353.1
Pyruvate dehydrogenase E1 component alpha subunit.
 0.998
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.998
SFA72167.1
Dihydrolipoamide dehydrogenase.
 
 0.989
SFB00377.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.983
SFB18131.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 0.983
SFA80576.1
2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.974
SFB18147.1
Dihydrolipoamide dehydrogenase.
 
 0.969
SFB00389.1
Dihydrolipoamide dehydrogenase.
 
 0.966
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
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