Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
polCDNA polymerase-3 subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1430 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.940
SFB29786.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.929
SFA70009.1
DNA polymerase III, delta subunit.
    
 0.902
SFB24931.1
DNA polymerase-3 subunit alpha.
    
 0.875
SFB21489.1
DNA polymerase-3 subunit epsilon.
    
 0.844
SFB31439.1
DNA polymerase-3 subunit delta'.
   
 0.840
dinG
ATP-dependent DNA helicase DinG; 3'-5' exonuclease.
    
  0.784
rimP
Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.731
SFA69844.1
Putative HD superfamily hydrolase of NAD metabolism.
  
     0.727
tmcAL
Predicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
     0.712
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
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