STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxSS-ribosylhomocysteine lyase /quorum-sensing autoinducer 2 (AI-2) synthesis protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (155 aa)    
Predicted Functional Partners:
mtnN
Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.991
SFA80865.1
Cystathionine gamma-lyase.
  
 
 0.966
SFB28313.1
Methionine synthase II (cobalamin-independent).
 
  
 0.965
SFA80848.1
O-acetylserine dependent cystathionine beta-synthase.
  
 
 0.901
SFA97169.1
O-acetylhomoserine sulfhydrylase.
     
 0.883
SFA80816.1
Putative AdoMet-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase.
     0.768
SFB31959.1
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.740
SFB28985.1
PAS domain S-box-containing protein/diguanylate cyclase (GGDEF) domain-containing protein.
     
 0.690
SFA77690.1
Flagellar motor switch protein FliG.
    
 
 0.687
SFB07074.1
Homoserine dehydrogenase.
     
 0.680
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
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