Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SFB04462.1Thioredoxin; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.840
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.793
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
    
 
 0.706
SFB24268.1
Thioredoxin; Belongs to the thioredoxin family.
  
  
 0.674
SFB04374.1
Glutaredoxin-related protein.
  
 0.645
SFA96006.1
Glutamate synthase (NADPH/NADH) large chain.
   
 
 0.624
SFB04475.1
Putative membrane protein.
       0.581
SFA73390.1
Thioredoxin reductase (NADPH).
  
 0.540
SFA91371.1
Thioredoxin reductase (NADPH).
  
 0.540
SFA89063.1
Thioredoxin reductase (NADPH).
  
 0.540
Your Current Organism:
Lentibacillus halodurans
NCBI taxonomy Id: 237679
Other names: Bacillaceae bacterium 8-1, CGMCC 1.3702, DSM 18342, L. halodurans, Lentibacillus halodurans Yuan et al. 2007, strain 8-1
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